MyISAM plus INNODB enable query cache?

We have 2GB of MyISAM plus 2GB INNODB data. Running MariaDB 10.* Should we enable or disable query_cache ?

Answer Answered by Harald Reindl in this comment.

nobody but you can answer that question - if you have more reads the writes on the same tables: yes - but why don't you just try it and get "mysqltuner" which will tell you something about hit rates

if you have a table which is permanently changed - no but then RTFM and disable the cache in the relevant queries itself which can not benefit from it

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